Indomethacin

My application for individual benefits with Blue Cross was declined because of my AS diagnosis. This results in my inability to afford Enbrel, which I anticipate needing soon because of the frequency of my flares. I have been using Indomethacin as a substitute; it is readily prescribed by family physicians and is effective at reducing the inflammation that causes moderate to severe pain. Here is some information on this medication for those interested in considering this drug:

Indomethacin is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation. Indomethacin comes as a capsule, an extended-release (long-acting) capsule, and a suspension to take by mouth and as a suppository to be used rectally. Indomethacin capsules, liquid, and suppositories usually are taken two to four times a day.

Indomethacin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• headache
• dizziness
• vomiting
• diarrhea
• constipation
• irritation of the rectum
• constant feeling of the need to empty the bowel
• ringing in the ears

Some side effects can be serious.

People who take nonsteroidal anti-inflammatory medications (NSAIDs) (other than aspirin) such as indomethacin may have a higher risk of having a heart attack or a stroke than people who do not take these medications. These events may happen without warning and may cause death. This risk may be higher for people who take NSAIDs for a long time.

I personally have not experienced any of the above side effects, except for ringing in the ears, which has been uncommon.